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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGRF2
All Species:
12.73
Human Site:
S848
Identified Species:
31.11
UniProt:
O14827
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14827
NP_008840.1
1237
140764
S848
A
A
D
T
T
E
L
S
P
C
R
S
P
S
T
Chimpanzee
Pan troglodytes
XP_517672
1237
140775
S848
A
A
D
T
T
E
L
S
P
C
R
S
P
S
T
Rhesus Macaque
Macaca mulatta
XP_001108408
514
59608
E168
R
Q
Q
I
E
D
G
E
I
E
I
E
R
L
K
Dog
Lupus familis
XP_852734
1350
152162
S850
A
V
D
S
T
D
L
S
P
C
R
S
P
S
T
Cat
Felis silvestris
Mouse
Mus musculus
P70392
1189
135649
V829
A
D
S
A
H
C
S
V
S
P
A
S
A
F
A
Rat
Rattus norvegicus
Q99JE4
1190
135808
A829
V
A
D
S
T
H
C
A
V
S
P
A
S
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510010
1242
141041
M853
P
P
A
D
A
A
E
M
S
P
C
R
S
P
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CEA7
1244
141569
S855
A
S
E
P
G
E
I
S
P
C
R
S
P
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122143
690
76494
L344
R
F
L
S
I
D
F
L
N
T
F
L
L
T
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780300
1211
137984
M842
V
V
V
T
S
S
R
M
S
T
R
R
S
S
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
31.3
87.1
N.A.
91.1
91.2
N.A.
91.2
N.A.
N.A.
85.4
N.A.
N.A.
25.4
N.A.
48.5
Protein Similarity:
100
99.7
36.2
89.2
N.A.
93.5
93.6
N.A.
95.1
N.A.
N.A.
91.6
N.A.
N.A.
37
N.A.
64.7
P-Site Identity:
100
100
0
80
N.A.
13.3
20
N.A.
0
N.A.
N.A.
66.6
N.A.
N.A.
0
N.A.
20
P-Site Similarity:
100
100
6.6
93.3
N.A.
13.3
46.6
N.A.
6.6
N.A.
N.A.
86.6
N.A.
N.A.
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
30
10
10
10
10
0
10
0
0
10
10
10
10
10
% A
% Cys:
0
0
0
0
0
10
10
0
0
40
10
0
0
0
10
% C
% Asp:
0
10
40
10
0
30
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
10
30
10
10
0
10
0
10
0
0
0
% E
% Phe:
0
10
0
0
0
0
10
0
0
0
10
0
0
10
10
% F
% Gly:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
10
0
10
0
10
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
0
10
0
0
0
30
10
0
0
0
10
10
10
0
% L
% Met:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
10
10
0
10
0
0
0
0
40
20
10
0
40
10
0
% P
% Gln:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
20
0
0
0
0
0
10
0
0
0
50
20
10
0
0
% R
% Ser:
0
10
10
30
10
10
10
40
30
10
0
50
30
50
10
% S
% Thr:
0
0
0
30
40
0
0
0
0
20
0
0
0
10
40
% T
% Val:
20
20
10
0
0
0
0
10
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _